Indolent zygomycosis associated with deferoxamine chelation therapy
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چکیده
منابع مشابه
Indolent zygomycosis associated with deferoxamine chelation therapy.
This paper describes a 71-year-old man with myelodysplasia who required multiple transfusions and subsequent deferoxamine chelation therapy and who then developed indolent cutaneous and probable pulmonary infection with Rhizopus species. The patient did not have rapidly progressive infection as has been described in almost all previously reported deferoxamine-treated patients with zygomycosis. ...
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Iron overload is the primary cause of mortality and morbidity in thalassemia major despite advances in chelation therapy. We performed a pilot clinical trial to evaluate the safety and efficacy of combined therapy with deferasirox (DFX, 20-30 mg/kg daily) and deferoxamine (DFO, 35-50mg/kg on 3-7 days/week) in 22 patients with persistent iron overload or organ damage. In the 18 subjects completi...
متن کاملMucormycosis Associated With Deferoxamine Therapy After allogeneic Bone Marrow Transplantation.
Mucormycosis is an uncommon acute and often fatal opportunistic fungal infection that is classically seen with poorly controlled diabetes mellitus with acidosis, acute leukemia, or other immunosuppressive conditions. A relatively new association of mucormycosis occurring in patients with iron and aluminum excess who receive deferoxamine therapy has been reported with increasing frequency. While...
متن کاملMucormycosis: association with deferoxamine therapy.
M ucormycosis is an uncommon acute and often fatal opportunistic fungal infection that usually occurs in patients with poorly controlled diabetes mellitus, acute leukemias, or other immunosuppressive conditions [1,2]. A new association, that of mucormycosis occurring in patients receiving deferoxamine therapy for iron or aluminum excess, has been reported with increasing frequency since 1986 [3...
متن کاملUltrafiltration studies in vitro of serum aluminum in dialysis patients after deferoxamine chelation therapy.
Using gel filtration chromatography, we evaluated aluminum bound to albumin, transferrin, and other plasma proteins in the serum of patients on maintenance hemodialysis. The proportion of dialyzable aluminum, as determined by selective membrane ultrafiltration and flameless atomic absorption spectrometry, increased by more than fourfold on treatment with the metal chelator, deferoxamine. This u...
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ژورنال
عنوان ژورنال: Mycoses
سال: 1994
ISSN: 0933-7407,1439-0507
DOI: 10.1111/j.1439-0507.1994.tb00394.x